| Modernatx, Inc. | Cambridge | MA | $7.74B |
| Alliance For Energy Innovation, LLC | Lakewood | CO | $5.81B |
| Emergent Product Development Gaithersburg Inc. | Gaithersburg | MD | $1.34B |
| Cherokee Nation Strategic Programs, L.L.C. | Tulsa | OK | $929M |
| PPD Development LP | Wilmington | NC | $811M |
| Axle Informatics, LLC | North Bethesda | MD | $799M |
| Tunnell Consulting Inc. | Berwyn | PA | $400M |
| Mapp Biopharmaceutical, Inc. | San Diego | CA | $369M |
| Basilea Pharmaceutica International Ltd. Allschwil | Allschwil | | $172M |
| Laulima Government Solutions, LLC | Orlando | FL | $170M |
| Ginkgo Bioworks, Inc. | Boston | MA | $166M |
| Goldbelt Professional Services, LLC | Chesapeake | VA | $162M |
| The Broad Institute, Inc. | Cambridge | MA | $154M |
| Priority One Services, Inc. | Alexandria | VA | $139M |
| Abss Solutions Inc. | Upper Marlboro | MD | $138M |
| Venatorx Pharmaceuticals Inc. | Chadds Ford | PA | $136M |
| Kaleo, Inc. | Glen Allen | VA | $134M |
| Commonwealth Scientific And Industrial Research Organisation | Acton | | $117M |
| Crossject Sa | Dijon | | $109M |
| Paratek Pharmaceuticals, Inc. | King Of Prussia | PA | $109M |
| Vedanta Biosciences, Inc. | Cambridge | MA | $91.8M |
| Advanced Bioscience Laboratories, Inc. | Potomac | MD | $79.8M |
| Public Health Vaccines LLC | Elkridge | MD | $79M |
| Infinity Biologix LLC | Piscataway | NJ | $75.3M |
| Battelle National Biodefense Institute, LLC | Fort Detrick | MD | $74.8M |
| Locus Biosciences Inc. | Morrisville | NC | $70.8M |
| Vir Biotechnology, Inc. | San Francisco | CA | $65.9M |
| Tempus Ai, Inc. | Chicago | IL | $65.4M |
| Cellphire, Inc. | Rockville | MD | $63.1M |
| 4J Therapeutics Inc. | Palo Alto | CA | $63.1M |
| Cidara Therapeutics Inc. | San Diego | CA | $58.1M |
| Revagenix Inc. | San Mateo | CA | $52.1M |
| Lovelace Biomedical Research Institute | Albuquerque | NM | $48.2M |
| Experimental Pathology Laboratories, Inc. | Sterling | VA | $46.6M |
| Nanohmics Inc. | Austin | TX | $45.4M |
| Visby Medical, Inc. | San Jose | CA | $41.5M |
| Eitr Biologics, Inc. | San Diego | CA | $39.6M |
| La Jolla Institute For Immunology | La Jolla | CA | $39.4M |
| New York Genome Center, Inc. | New York | NY | $36.8M |
| Coriell Institute For Medical Research, Inc. | Camden | NJ | $36.7M |
| Metabolon, Inc. | Morrisville | NC | $35.9M |
| Health Decisions, Inc. | Morrisville | NC | $35.7M |
| Advanced Regenerative Manufacturing Institute Inc. | Manchester | NH | $34.2M |
| Invirsa, Inc. | Columbus | OH | $33.5M |
| Apiject Systems America, Inc. | Stamford | CT | $33.5M |
| Regenstrief Institute Inc. | Indianapolis | IN | $32.9M |
| Gigagen Inc. | San Carlos | CA | $29.6M |
| Chromologic LLC | Monrovia | CA | $29.5M |
| Dnanexus, Inc. | Mountain View | CA | $28.9M |
| Jackson Laboratory | Bar Harbor | ME | $25.9M |
| Prenosis, Inc. | Chicago | IL | $25.1M |
| Georgia State University Research Foundation Inc. | Atlanta | GA | $24.1M |
| Flambeau Diagnostics LLC | Madison | WI | $23.9M |
| Pattern Bioscience, Inc. | Austin | TX | $22.5M |
| Sapphiros LLC | Groton | MA | $22.4M |
| Spring Mill Pharma Incorporated | Marlborough | NH | $21.8M |
| Bioaegis Therapeutics Inc. | Morristown | NJ | $20.7M |
| Osivax | Lyon | | $20.2M |
| Zcore Business Solutions, Inc. | Round Rock | TX | $18.7M |
| Somalogic Operating Co. Inc. | Boulder | CO | $15.9M |
| Microbiotix, Inc. | Worcester | MA | $15.7M |
| Genscript USA Inc. | Piscataway | NJ | $14.7M |
| Vitrivax, Inc. | Boulder | CO | $14.5M |
| Hopo Therapeutics, Inc. | Emeryville | CA | $14.2M |
| Abviro LLC | Bethesda | MD | $13.6M |
| Blacksmith Medicines, Inc. | San Diego | CA | $13M |
| Enalare Therapeutics Inc. | Mullica Hill | NJ | $13M |
| Biospyder Technologies, Inc. | Carlsbad | CA | $12.8M |
| Intravacc B.v. | Bilthoven | | $12.8M |
| Transnetyx, Inc. | Cordova | TN | $12.8M |
| Military Health Research Foundation, Inc. | Laurel | MD | $12M |
| Mediwound Ltd. | Yavne | | $11.5M |
| Aligos Therapeutics Inc. | South San Francisco | CA | $11.3M |
| Eveliqure Biotechnologies GMBH | Wien | | $11.3M |
| Primmune Therapeutics, Inc. | Carlsbad | CA | $11.2M |
| Integral Molecular Inc. | Philadelphia | PA | $11.1M |
| The Translational Genomics Research Institute | Phoenix | AZ | $10.9M |
| Spaulding Clinical Research, LLC | West Bend | WI | $10.9M |
| Versatope Therapeutics Inc. | Lowell | MA | $10.9M |
| Inimmune Corp. | Missoula | MT | $10.2M |
| Codagenix Inc. | Farmingdale | NY | $10M |
| Sachi Bioworks, Inc. | Erie | CO | $9.95M |
| Lasso Informatics US Inc. | Newark | DE | $9.85M |
| Pathogendx Inc. | Tucson | AZ | $9.51M |
| Polynovo Biomaterials Pty Ltd. | Port Melbourne | VICTORIA | $9.51M |
| National Institute For Pharmaceutical Technology & Education Inc. | Minneapolis | MN | $9.46M |
| Vaxart Biosciences Inc. | South San Francisco | CA | $9.27M |
| Lumos Diagnostics, Inc. | Carlsbad | CA | $9.18M |
| HDT Bio Corp. | Seattle | WA | $9.11M |
| Greater Los Angeles Veterans Research And Education Foundation | Los Angeles | CA | $9.1M |
| Molecular Express, Inc. | Rancho Dominguez | CA | $8.74M |
| Clear Scientific, LLC | Cambridge | MA | $8.67M |
| Scripps Research Institute | La Jolla | CA | $8.57M |
| Ridgeback Biotherapeutics LP | Coconut Grove | FL | $8.4M |
| Gintech LLC | Mesa | AZ | $8.08M |
| Vaxxas Pty Ltd. | Hamilton | | $7.87M |
| Research Foundation For The State University Of New York, The | Albany | NY | $7.61M |
| Nirsense, Inc. | Richmond | VA | $7.48M |
| Dna Hive LLC | Rockville | MD | $7.46M |
| Uk Health Security Agency | Salisbury | | $7.33M |